Actiponin®

Figure (1) Damulin A, Figure (2) Damulin B

Actiponin®

Actiponin® boosts cellular oxidation of fatty acids via the activation of AMPK. We further proved that Actiponin® reduces the three different types of body fat layer in human by up to 11% in the preclinical and clinical trials (Obesity 22:63). Actiponin® is a patented neutraceuticals from Gynostemma pentaphyllum leaf, containing 1.2% of Damulin A, the active saponin component. Actiponin® contains Damulin A  and Damulin B, which together demonstrate 10 times better efficacy in activating AMPK, in comparison to other standardized extracts from G. pentaphyllum.

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Gynostemma pentaphyllum

Gynostemma pentaphyllum is an adaptogenic and well-known herb of ever-live young used in Korea, Japan, and China for more than 500 years. It has been known to restore physiological balances (homeostasis) by modulating the blood pressure, cholesterol level in blood, inflammation, mental stability, physical endurance, and longevity of human kind (Jiaogulan (Gynostemma pentaphyllum); China’s “Immortality” Herb, M. Blumert and J. Liu, 2000, Torchlight Publishing, Inc. USA).

Various Name

Korea: Dungulcha/Dolwe

Japan: Amachazuru

China: Jiaogulan

Actiponin® has been distributed to the global companies, CellMark, Life Extension, Piping Rock, Horbäach, Alpha Lions, Kardashian’s group Lemme and others as well as more than fifty companies in Korea.